Beyond Toll-Like Receptor 9: Interactions Between Plasmacytoid Dendritic Cells and Aspergillus Fumigatus: A Dissertation
نویسندگان
چکیده
...................................................................................... viii List of Tables.................................................................................. xiv List of Figures................................................................................. xv List of Abbreviations......................................................................... xvii Chapter I: Introduction..................................................................... 1.1 Aspergillus.................................................................... 1.2 The Pathogen A. fumigatus................................................. 1.3 Overview of the Immune System......................................... 1.4 Toll-Like Receptors......................................................... 1.5 Host Immune Responses against A. fumigatus.......................... 1.6 Thesis Overview............................................................ 1
منابع مشابه
Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA.
Phagocytic defenses are critical for effective host defenses against the opportunistic fungal pathogen Aspergillus fumigatus. Previous studies found that following challenge with A. fumigatus, Toll-like receptor 9 (TLR9) knockout mice survived longer than wild-type mice. However, the mechanism responsible was not defined. Here we demonstrate that A. fumigatus contains unmethylated CpG sequences...
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